Terry Teachout mentioned recently that he was going to San Francisco and staying in a boutique hotel.
His hotel was the Hotel Adagio, part of the Joie de Vivre Hospitality group. JDV hsa got a great looking website, and is distinguished by a gimmick of matching your personality to a hotel in their group via their Hotel Matchmaker, Yvette.
It also has a section where "locals talk about this neighborhood" - in this case Donald Graves.
I like it. It seems to give you a good insiders view about good places to go, see and eat at. Helps in getting restaurant reservations before you hit town.
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